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Huntingtin and the molecular pathogenesis of Huntington's disease: Fourth in Molecular Medicine Review Series: EMBO reports: Vol 5, No 10 » Oct 1, 2004… Huntington's disease (HD) is a late‐onset neurodegenerative disorder that is caused by a CAG repeat expansion in the IT15 gene. Embopress.org

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Huntington aggregates may not predict neuronal death in Huntington's disease - PubMed » The mechanism by which polyglutamine expansion in Huntington's disease (HD) results in selective neuronal degeneration remains unclear. We previously reported that the immunohistochemical distribution of N-terminal huntingtin in HD does not correspond to the severity of neuropathology, such that sig … Pubmed.ncbi.nlm.nih.gov

Huntington's disease gene (IT15) is widely expressed in human and rat tissues - PubMed » Huntington's Disease (HD) is notable for selective neuronal vulnerability in the basal ganglia and cerebral cortex. We have investigated in human and rodent tissues the expression of the gene (IT15) whose mutation causes HD. IT15 is widely expressed, with highest levels of expression in brain, but a … Pubmed.ncbi.nlm.nih.gov

Mutant Huntingtin in Glial Cells Exacerbates Neurological Symptoms of Huntington Disease Mice » Huntington disease (HD) is caused by an expansion of the polyglutamine (polyQ) repeat (>37Q) in huntingtin (htt), and age of onset is inversely correlated with the length of the polyQ repeat. Mutant htt with expanded polyQ is ubiquitously expressed… Pmc.ncbi.nlm.nih.gov

News Release - The Huntington Acquires the Papers of Dana Gioia, Former California Poet Laureate and Chair of the National Endowment of the Arts | The Huntington » The Huntington Library, Art Museum, and Botanical Gardens announced today that it has acquired the papers of Dana Gioia, an internationally acclaimed poet and writer who served as the chair of the National Endowment for the Arts Huntington.org

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